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Resumo Este estudo objetivou identificar a prevalência e os fatores associados ao comportamento de risco para transtorno alimentar entre estudantes universitários da área da saúde. Trata-se de um estudo epidemiológico de corte transversal, analítico, exploratório e abordagem quantitativa. Os dados foram obtidos por meio de um questionário que abordava as características sociodemográficas, econômicas e hábitos de vida. Para avaliar o comportamento de risco para transtorno alimentar (variável dependente), utilizou-se o Eating Attitudes Test(EAT-26). Foram coletadas ainda as medidas antropométricas. Utilizou-se o modelo de regressão de Poisson para obter estimativas do efeito das variáveis no comportamento de risco para transtornos alimentares. Participou do estudo 364 universitários, com idade média de 22,8±4,7 anos. Foi possível observar prevalência de comportamento de risco para transtorno alimentar em 21,7% dos investigados. As variáveis que se mostraram associadas à maior prevalência do desfecho investigado na análise ajustada foram: presença de insatisfação com a imagem corporal (RP=2,63; IC 95%: 1,68-4,10), realizar tratamento para perder peso (RP=1,64; IC 95%: 1,05-2,57) e risco de doença cardiovascular avaliado através da circunferência da cintura (RP=1,54; IC 95%: 1,02-2,31). Conclui-se que a prevalência de comportamento de risco para transtorno alimentar entre os participantes do estudo foi elevada e hábitos de vida e perfil antropométrico são fatores que se associaram ao desfecho observado.

Abstract This study aimed to identify the prevalence and factors associated with risk behavior for eating disorders among university students in the health area. This is an epidemiological cross-sectional, analytical, exploratory study with a quantitative approach. Data were obtained through a questionnaire that addressed sociodemographic and economic characteristics and lifestyle habits. To assess risk behavior for eating disorders (dependent variable), the Eating Attitudes Test (EAT-26) was used. Anthropometric measurements were also collected. The Poisson regression model was used to obtain estimates of the effect of variables on risk behavior for eating disorders. 364 university students participated in the study, with a mean age of 22.8±4.7 years. It was possible to observe the prevalence of risk behavior for eating disorders in 21.7% of those investigated. The variables that were associated with a higher prevalence of the investigated outcome in the adjusted analysis were: presence of dissatisfaction with body image (PR=2.63; 95%CI: 1.68-4.10), undergoing treatment to lose weight (PR=1.64; 95%CI: 1.05-2.57) and risk of cardiovascular disease assessed through waist circumference (PR=1.54; 95%CI: 1.02-2.31). It is concluded that the prevalence of risk behavior for eating disorders among the study participants was high and lifestyle habits and anthropometric profile are factors that were associated with the observed outcome.

https://doi.org/10.15309/23psd240308

[SciELO Preprints] - Open Infrastructures in action: DataCite and ORCID
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Cardoso, Ana Patricia Mejias, Gabriela Marín-Arraiza, Paloma Gomes Ferreira, Verónica

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Data de publicação: 2023-02-07

Resumo: En Es Pt

Openness, reliability, identifiability and interoperability of scientific information are increasingly relevant aspects for the scientific community and open research infrastructure. Within open research infrastructure, one of the pillars of Open Science, persistent identifiers are established as a main building block, enabling interoperability between entities such as authors, outputs and institutions. To consolidate and maintain best practices around them, DataCite and ORCID have worked together since their early days and have fostered the development of communities of practice in the adoption of open persistent identifiers. This text frames identifiers within the framework of Open Science and the FAIRification of scientific information. It also presents the joint trajectory of DataCite and ORCID and the concept of communities of practice applied to open persistent identifiers. Finally, it explores the work developed in Ibero-America and possible future scenarios.

La apertura, fiabilidad, identificación e interoperabilidad de la información científica son aspectos cada vez más relevantes para la comunidad científica y la infraestructura abierta de investigación. Dentro de la infraestructura abierta de investigación, uno de los pilares de la Ciencia Abierta, los identificadores persistentes se establecen como un bloque principal, permitiendo la interoperabilidad entre entidades como autores, producción e instituciones. Para consolidar y mantener buenas prácticas en torno a ellos, DataCite y ORCID han trabajado conjuntamente desde su creación y han fomentado el desarrollo de comunidades de práctica en la adopción de identificadores persistentes abiertos. Este texto encuadra los identificadores dentro del marco de la Ciencia Abierta y la FAIRificación de la información científica. Asimismo, presenta la trayectoria conjunta de DataCite y ORCID y el concepto de comunidades de práctica aplicado a identificadores persistentes abiertos. Por último, explora el trabajo desarrollado en Iberoamérica y posibles escenarios futuros.

A abertura, confiabilidade, identificabilidade e interoperabilidade das informações científicas são aspectos cada vez mais relevantes para a comunidade científica e para a infraestrutura aberta de pesquisa. Dentro da infraestrutura aberta de pesquisa, um dos pilares da Ciência Aberta, os identificadores persistentes são estabelecidos como um bloco de construção principal, permitindo a interoperabilidade entre entidades como autores, produção e instituições. Para consolidar e manter boas práticas em torno deles, DataCite e ORCID têm trabalhado juntos desde seu início e fomentado o desenvolvimento de comunidades de prática na adoção de identificadores persistentes abertos. Este texto enquadra os identificadores no âmbito da Ciência Aberta e da FAIRificação da informação científica. Também apresenta a trajetória conjunta de DataCite e ORCID e o conceito de comunidades de prática aplicado a identificadores abertos persistentes. Finalmente, explora o trabalho desenvolvido na Ibero-América e os possíveis cenários futuros.

https://doi.org/10.1590/SciELOPreprints.5467

Fatores associados à taxa de doações efetivas de órgãos sólidos por morte encefálica: uma análise espacial nas Unidades Federativas do Brasil (2012-2017)
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Assis, Paloma Carpena de

; Favoretto, Cássia Kely

; Balbinotto Neto, Giácomo

; Gomes, Carlos Eduardo

Estudos Econômicos (São Paulo)

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2023, Volume 53 Nº 2 Páginas 257 - 303

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract This study analyzes the factors associated with the effective solid organ donation rate (heart, lungs, kidneys, liver, and pancreas) due to brain death in the Brazilian Federative Units (UF) from 2012 to 2017. For this purpose, Exploratory Spatial Data Analysis and the Spatial Durbin model with panel data were used. The conditioning factors used were divided into sociodemographic and health management. The existence of large regional disparities in the donation process among these areas was evidenced, with spatial clusters of high-high type in the southern region of the country. The results showed that population density positively affected these donations in the unit of analysis. This same signal was obtained when considering the impact of the variables lagged density, lagged schooling, and the effects of spatial spillovers. The lagged population aging rate negatively affected these donations in the unit of analysis, in addition to having indirect and total negative results on the donation rate in neighboring units. When considering the ethnic composition, through the proportion of non-whites, it was observed that the higher this proportion in each UF, the lower donation rate in that same unit, confirmed by the direct effect. The sign of this lagged explanatory factor and the indirect effect was negative. The emergency breathing rate proved to be important for the growth of the donation rate in the analyzed areas. The lag in the rate of beds in the Intensive Care Unit (UTI) had a negative effect on donations and the spillover effects (indirect and total effects) followed the same impact direction. The rate of organ transplantation teams negatively affected these donations in the unit of analysis; however, the effect of neighbors was positive, with a positive relationship in the indirect effect and a negative relationship in the direct one. The rate of deaths from neurological causes in each UF positively affected its donations, but this factor in neighboring units negatively affected the dependent variable, in addition to the direction of the direct effect being positive and the indirect effect being negative. The dummies referring to public policies that created the Organ Procurement Organizations (OPO’s) and the Intra-Hospital Commissions for the Donation of Organs and Tissues for Transplantation (CIHDOTT’s) showed positive total effects, indicating their importance in this process. It was concluded that the geographic and temporal behavior of solid organ donations in the federative units were explained by the sociodemographic and management conditions discussed. Effective decisions by the managers of this system, based on evidence, are necessary to improve the structural and dynamic performance of the donation process, especially in relation to regional differences in the supply of organs in the country.

Resumo Este estudo analisa os fatores associados à taxa de doações efetivas de órgãos sólidos (coração, pulmões, rins, fígado e pâncreas) por morte encefálica nas Unidades Federativas (UF) do Brasil, no período de 2012 a 2017. Para tanto, fez-se uso da Análise Exploratória de Dados Espaciais e do modelo de Durbin Espacial com dados em painel. Os condicionantes usados foram divididos em sociodemográficos e de gestão em saúde. Evidenciou-se a existência de grandes disparidades regionais no processo de doação nestas áreas, com agrupamentos espaciais do tipo Alto-Alto na região Sul do país. Os resultados mostraram que a densidade populacional afetou positivamente essas doações na unidade de análise. Esse mesmo sinal foi obtido ao se considerar o impacto das variáveis densidade defasada, escolaridade defasada e os efeitos dos transbordamentos espaciais. A taxa de envelhecimento populacional defasada afetou negativamente essas doações na unidade de análise, além de apresentar resultados negativos indiretos e total sobre a taxa de doação nas unidades vizinhas. Ao se considerar a composição étnica, por meio da proporção de não brancos, observou-se que quanto maior for essa proporção em determinada UF, menor é taxa de doação nessa mesma unidade, confirmada pelo efeito direto. O sinal desse fator explicativo defasado e do efeito indireto foi negativo. A taxa de respiradores de emergência mostrou-se importante para o crescimento da taxa de doação nas áreas analisadas. A defasagem da taxa de leitos em Unidade de Terapia Intensiva (UTI) teve efeito negativo sobre as doações e os efeitos spillover (efeitos indireto e total) seguiram a mesma direção de impacto. A taxa de equipes transplantadoras de órgãos afetou negativamente essas doações na unidade de análise, contudo, o efeito dos vizinhos foi positivo, observando-se relação positiva no efeito indireto e negativa no direto. A taxa de mortes por causas neurológicas de uma determinada UF afetou de forma positiva as suas doações, mas esse fator nas unidades vizinhas afetou negativamente a variável dependente, além da direção do efeito direto ser positiva e do indireto ser negativa. As dummies referentes às políticas públicas que criaram as Organizações de Procura de Órgãos (OPO’s) e as Comissões Intra-Hospitalares de Doação de Órgãos e Tecidos para Transplante (CIHDOTT’s) mostraram efeitos totais positivos, indicando a importância delas nesse processo. Concluiu-se que o comportamento geográfico e temporal das doações de órgãos sólidos nas unidades federativas foram explicados pelos condicionantes sociodemográficos e de gestão abordados. Decisões efetivas dos gestores desse sistema, com base em evidências, são necessárias para melhorar o desempenho estrutural e dinâmico do processo de doação, especialmente, em relação às diferenças regionais na oferta desses órgãos no país.

https://doi.org/10.1590/1980-53575322pcgc

The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal
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Lamas, Carlos José Einicker

; Fachin, Diego Aguilar

; Falaschi, Rafaela Lopes

; Alcantara, Daniel Máximo Correa de

; Ale-Rocha, Rosaly

; Amorim, Dalton de Souza

; Araújo, Maíra Xavier

; Ascendino, Sharlene

; Baldassio, Letícia

; Bellodi, Carolina Ferraz

; Bravo, Freddy

; Calhau, Julia

; Capellari, Renato Soares

; Carmo-Neto, Antonio Marcelino do

; Cegolin, Bianca Melo

; Couri, Márcia Souto

; Carvalho, Claudio José Barros de

; Dios, Rodrigo de Vilhena Perez

; Falcon, Aida Vanessa Gomez

; Fusari, Livia Maria

; Garcia, Carolina de Almeida

; Gil-Azevedo, Leonardo Henrique

; Gomes, Marina Morim

; Graciolli, Gustavo

; Gudin, Filipe Macedo

; Henriques, Augusto Loureiro

; Krolow, Tiago Kütter

; Mendes, Luanna Layla

; Limeira-de-Oliveira, Francisco

; Maia, Valéria Cid

; Marinoni, Luciane

; Mello, Ramon Luciano

; Mello-Patiu, Cátia Antunes de

; Morales, Mírian Nunes

; Oliveira, Sarah Siqueira

; Patiu, Claudemir

; Proença, Barbara

; Pujol-Luz, Cristiane Vieira de Assis

; Pujol-Luz, José Roberto

; Rafael, José Albertino

; Riccardi, Paula Raile

; Rodrigues, João Paulo Vinicios

; Roque, Fabio de Oliveira

; Sallum, Maria Anice Mureb

; Santis, Marcelo Domingos de

; Santos, Charles Morphy Dias dos

; Santos, Josenilson Rodrigues dos

; Savaris, Marcoandre

; Shimabukuro, Paloma Helena Fernandes

; Silva, Vera Cristina

; Schelesky-Prado, Daniel de Castro

; Silva-Neto, Alberto Moreira da

; Camargo, Alexssandro

; Sousa, Viviane Rodrigues de

; Urso-Guimarães, Maria Virginia

; Wiedenbrug, Sofia

; Yamaguchi, Carolina

; Nihei, Silvio Shigueo

Revista Brasileira de Entomologia

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2023, Volume 67 Nº 4 elocation e20230051

Resumo: En | Texto: En | PDF: En

ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists.

https://doi.org/10.1590/1806-9665-rbent-2023-0051

Development and validation of an instrument for nursing consultation with pediatric patients in the preoperative period
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Acioly, Paloma Gonçalves Martins

; Paiva, Eny Dórea

; Reis, Adriana Teixeira

; Gomes, Tatiana de Oliveira

; Silva, Luciana Rodrigues da

; Silva, Liliane Faria da

Revista da Escola de Enfermagem da USP

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2022, Volume 56 elocation e20210467

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Elaborar e validar um instrumento para consulta de enfermagem ao paciente pediátrico em pré-operatório. Método: Estudo metodológico, composto por cinco etapas: identificação dos diagnósticos de enfermagem, discussão e avaliação dos diagnósticos com enfermeiros da instituição, elaboração do instrumento, validação do conteúdo do instrumento com experts pela Técnica Delphi e reestruturação do instrumento. Foram utilizados o Conjunto de Dados Mínimos de Enfermagem, as necessidades humanas de Wanda Horta e as ligações NANDA-NOC-NIC como referencial teórico. Resultados: Em sua versão final, o instrumento contempla avaliação das necessidades humanas psicobiológicas, psicossociais e psicoespirituais, 38 diagnósticos de enfermagem, 65 intervenções, 113 atividades e 62 resultados de enfermagem. O instrumento obteve índice de validade de conteúdo entre 0,90 e 1,0 na primeira rodada, e sugestões, validadas na segunda rodada, obtendo concordância de 70 a 100%. Conclusão: O instrumento elaborado pode ser uma ferramenta para uso em consulta de enfermagem no pré-operatório infantil, conferindo maior assertividade nas ações de enfermagem a essa clientela.

ABSTRACT Objective: To develop and validate an instrument for nursing consultation with pediatric patients in the preoperative period. Method: This is a methodological study, consisting of five steps: identification of nursing diagnoses, discussion and evaluation of diagnoses with nurses from the institution, instrument development, instrument content validation with experts through the Delphi Technique, and instrument restructuring. The Nursing Minimum Data Set, Wanda Horta’s human needs, and the NANDA-NOC-NIC connections were used as theoretical framework. Results: In its final version, the instrument includes an assessment of psychobiological, psychosocial, and psychospiritual human needs, 38 nursing diagnoses, 65 nursing interventions, 113 nursing activities, and 62 nursing outcomes. The instrument obtained a content validity index between 0.90 and 1.0 in the first round, and suggestions, validated in the second round, obtained agreement from 70 to 100%. Conclusion: The instrument developed can be a tool for use in nursing consultations in the preoperative period for children, providing greater assertiveness to nursing actions for this clientele.

RESUMEN Objetivo: Elaborar y validar un instrumento para consulta de enfermería al paciente pediátrico en preoperatorio. Método: Estudio metodológico, compuesto por cinco etapas: identificación de los diagnósticos de enfermería, discusión y evaluación de los diagnósticos con enfermeros de la institución, elaboración del instrumento, validez del contenido del instrumento con expertos por la Técnica Delphi y reestructuración del instrumento. Se utilizaron el Conjunto de Datos Mínimos de Enfermería, las necesidades humanas de Wanda Horta y la nomenclatura NANDA-NOC-NIC. Resultados: En su versión final, el instrumento contempla evaluación de las necesidades humanas psicobiológicas, psicosociales y psicoespirituales, 38 diagnósticos de enfermería, 65 intervenciones, 113 actividades y 62 resultados de enfermería. El instrumento obtuvo índice de validez de contenido entre 0,90 y 1,0 70 en la primera etapa, y sugerencias, validadas en la segunda etapa que obtuvieron concordancia de 70 a 100%. Conclusión: El instrumento elaborado puede ser una herramienta para uso en consulta de enfermería en el preoperatorio infantil, proporcionando más seguridad en las acciones de enfermería a ese público.

https://doi.org/10.1590/1980-220x-reeusp-2021-0467

Adverse reactions caused by antimicrobials in hospitalized pediatric patients: causality and avoidability analysis
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Alexandre Júnior, Ronaldo Gomes

; Lima, Paloma Araújo de

; Portela, Mileyde Ponte

; Lima, João Lucas de Farias

; Lima, Elisangela Costa

; Fonteles, Marta Maria de França

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e20799

Resumo: En | Texto: En | PDF: En

Abstract In pediatrics, drug therapy is commonly performed through adaptations of the dosage forms to adult use, increasing the risk of adverse drug reactions. In this context, studies assessing the severity and avoidability of the adverse reactions in children, especially those caused by antimicrobials, are still scarce. This work aimed to investigate suspected antimicrobial adverse reactions (ATM-ADRs) in pediatric patients admitted to a public hospital in northeastern Brazil, focusing on causality and avoidability analysis. A cohort study was carried out over a period of six months in a 64-bed pediatric unit. The incidence of suspected adverse reactions caused by antimicrobials was 14.65%. Most reactions were rated as probable (89.13%), with moderate severity (84.78%) and possibly avoidable (45.65%). The analysis indicated that the use of a larger number of medications (p<0.0001) and longer hospital stay (p=0.004) were related to the occurrence of ATM-ADR. Our findings demonstrated that almost half of the suspected reactions could be prevented and that the antimicrobial’s clinical management is relevant in this context. Besides, increasingly accurate adverse reaction classification instruments are essential. These results can support the development of therapeutic guidelines addressed to a safe and effective pharmacotherapy in the pediatric area.

https://doi.org/10.1590/s2175-97902022000x20799

Impacto do Programa Academia da Saúde sobre a mortalidade por Hipertensão Arterial Sistêmica no estado de Pernambuco, Brasil
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Rodrigues, Bárbara Letícia Silvestre

; Silva, Rafaela Niels da

; Arruda, Rodrigo Gomes de

; Silva, Paloma Beatriz Costa

; Feitosa, Daíze Kelly da Silva

; Guarda, Flávio Renato Barros da

Ciência & Saúde Coletiva

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Dez 2021, Volume 26 Nº 12 Páginas 6199 - 6210

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste artigo foi avaliar o impacto do Programa Academia da Saúde sobre a mortalidade por Hipertensão Arterial Sistêmica no estado de Pernambuco, Brasil. Este estudo quase-experimental configura-se como uma avaliação de impacto de políticas públicas, desenvolvida através da aplicação do método do Pareamento por Escore de Propensão, nos anos de 2010 e 2017. Utilizou-se dados socioeconômicos, demográficos e epidemiológicos dos 89 municípios que implantaram o programa (tratados) e de outros 52 que não implantaram (controles). Os dados são oriundos do Departamento de Informática do SUS, Instituto Brasileiro de Geografia e Estatística e outras bases. O impacto do programa foi estimado através de um modelo logit, com o uso do algoritmo de pareamento Kernel. Os municípios tratados tiveram uma diminuição global de 12,8% na taxa de mortalidade por hipertensão, de 12,5% entre as pessoas de cor parda e de 13,1% em maiores de 80 anos. O teste de balanceamento atesta a robustez do modelo para explicar o impacto do programa sobre a mortalidade. A implementação do programa se mostrou efetiva para diminuir a taxa de mortalidade nos municípios tratados, indicando que o mesmo parece estar contribuindo para controlar o avanço das doenças crônicas não transmissíveis.

Abstract The aim of this paper was to analyze the impact of the Health Gym Program (HGP) on the Systemic Arterial Hypertension mortality rate in Pernambuco state, Brazil. This public policy impact analysis used a quasi-experimental approach which consisted of the application of Propensity Score Matching in the years 2010 and 2017. Socioeconomic, demographic, and epidemiological data of 89 municipalities that implemented HGP (treated) and 54 that did not (controls) were collected from the Brazilian Health Data Department, Brazilian Institute of Geography and Statistics, and other databases. The impact of HGP on hypertension mortality rate was estimated through a logit model using the Kernel algorithm. Treated municipalities presented a decrease of 12.8% in global hypertension mortality rate, 12.5% in brown-skinned people and 13.1% in those over 80 years of age. The balancing test attests to the robustness of the estimated model to explain the impact of the program on mortality due to hypertension. The implementation of the program proved to be effective in decreasing the mortality rate in the treated municipalities, indicating that it seems to contribute to controlling the progress of chronic non-communicable diseases.

https://doi.org/10.1590/1413-812320212612.32802020

Impacto do Programa Academia da Saúde sobre a mortalidade por Hipertensão Arterial Sistêmica no estado de Pernambuco, Brasil
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Rodrigues, Bárbara Letícia Silvestre

; Silva, Rafaela Niels da

; Arruda, Rodrigo Gomes de

; Silva, Paloma Beatriz Costa

; Feitosa, Daíze Kelly da Silva

; Guarda, Flávio Renato Barros da

Ciência & Saúde Coletiva

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Dez 2021, Volume 26 Nº 12 Páginas 6199 - 6210

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212612.32802020 1 downloads

Evaluation of Oxidative-Stress Pathway and Recovery of Sudden Sensorineural Hearing Loss
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Elias, Thaís Gomes Abrahão

; Monsanto, Rafael da Costa

; do Amaral, Jonatas Bussador

; Oyama, Lila Missae

; Maza, Paloma Korehisa

; Penido, Norma de Oliveira

International Archives of Otorhinolaryngology

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Set 2021, Volume 25 Nº 3 Páginas 428 - 432

Resumo: En | Texto: En | PDF: En

Abstract Introduction Although the pathogenesis of sudden sensorineural hearing loss (SSNHL) has been discussed in the literature, many unclear points remain. Several authors have hypothesized that oxidative stress plays a role in the pathogenesis of noise-related hearing loss, as well as in drug- and aging-related hearing loss. Reactive oxygen species (ROS) may contribute to the pathogenesis of SSNHL in a similar way as in cases of ototoxicity, noise-induced hearing loss and presbyacusis. Objective The aim of the present study was to find potential peripheral biomarkers to show the levels of oxidative stress in samples of peripheral blood collected from SSNHL patients with and withouth metabolic disease. Methods In total, 80 consecutive patients with SSNHL were evaluated in the otolaryngology emergency room and outpatient clinic of a tertiary hospital between May 2017 and May 2019. All patients underwent detailed anamnesis, physical examination, audiometry, magnetic resonance imaging (MRI) of the inner ears, and blood tests for serum lipids and plasma activity of thiobarbituric acid reactive species (TBARS). Results No significant effect of malondialdehyde (MDA) activity was observed regarding the hearing recovery of patients who developed SSNHL. Conclusion We did not observe a significant correlation between the concentration of TBARs in the peripheral blood or the presence of arterial hypertension and the severity of the initial hearing loss or the prognosis of hearing recovery in patients with SSNHL. The concentration of TBARs in the peripheral blood may not adequately represent the abnormalities that occur in the intracoclear environment.

https://doi.org/10.1055/s-0040-1714130 38 downloads

10.

Repercussões da Pandemia de COVID-19 na Prática Assistencial de um Hospital Terciário
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Almeida, André Luiz Cerqueira

; Santo, Thyago Monteiro do Espírito

; Mello, Maurício Silva Santana

; Cedro, Alexandre Viana

; Lopes, Nilson Lima

; Ribeiro, Ana Paloma Martins Rocha

; Mota, João Gustavo Cerqueira

; Mendes, Rodrigo Serapião

; Almeida, Paulo André Abreu

; Ferreira, Murilo Araújo

; Arruda, Diego Moreira

; Santos, Adriana Aguiar Pepe

; Rios, Vinícius Guedes

; Dantas, Maria Rosa Nascimento

; Silva, Viviane Almeida

; Silva, Marcos Gomes da

; Sampaio, Patrick Harrison Santana

; Guimarães, André Raimundo

; Santos Jr, Edval Gomes

Arquivos Brasileiros de Cardiologia

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Nov 2020, Volume 115 Nº 5 Páginas 862 - 870

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento Ainda não temos informações acerca do impacto da pandemia da COVID-19 sobre a atividade médica assistencial no Brasil. Objetivo Descrever as repercussões da pandemia da COVID-19 na rotina de atendimentos em um hospital terciário, referência regional em cardiologia e oncologia. Métodos Estudo de corte transversal. Foi realizado levantamento dos atendimentos no período de 23/03/2020 (fechamento do comércio local) até 23/04/2020 (P20) e comparado com o mesmo período em 2019 (P19).Resultados: Detectamos redução no número de consultas cardiológicas, teste ergométrico, Holter, monitorização ambulatorial da pressão arterial, eletrocardiograma e ecocardiograma (90%, 84%, 94%, 92%, 94% e 81%, respectivamente). Em relação à cirurgia cardíaca e cateterismo cardíaco, houve redução de 48% e 60%, respectivamente. Aumento no número de angioplastia transluminal coronária (33%) e de implante de marca-passo definitivo (29%). Houve 97 internamentos na UTI em P19, contra 78 em P20, redução de 20%. Diminuição dos atendimentos no pronto-socorro cardiológico (45%) e nos internamentos na enfermaria de cardiologia (36%). Houve diminuição nas consultas oncológicas de 30%. Sessões de quimioterapia reduziram de 1.944 para 1.066 (45%). Sessões de radioterapia diminuíram 19%. Conclusão A COVID-19 provocou redução considerável no número de consultas nos ambulatórios de cardiologia, oncologia e demais especialidades. Houve uma preocupante diminuição no número de cirurgias cardíacas e nas sessões de quimioterapia e radioterapia nas semanas iniciais da pandemia. A procura por atendimento no pronto-socorro cardiológico, assim como as internações na UTI e enfermaria cardiológicas, também reduziram, gerando preocupação acerca da evolução e prognóstico destes pacientes portadores de outras patologias, que não a COVID-19, nestes tempos de pandemia. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)

Abstract Background We still do not have information regarding the impact of the COVID-19 pandemic on medical care activity in Brazil. Objective To describe the repercussions of the COVID-19 pandemic on the care routine of a tertiary hospital, which is a regional reference in cardiology and oncology. Methods Cross-sectional cohort study. We conducted a survey of medical visits from March 23, 2020 (when local commerce was closed) to April 23, 2020 (P20), in comparison with the same period in 2019 (P19). Results We found decreases in the number of cardiology consultations, exercise tests, Holter, ambulatory blood pressure monitoring, electrocardiogram, and echocardiogram (90%, 84%, 94%, 92%, 94%, and 81%, respectively). In relation to cardiac surgery and cardiac catheterization, there were 48% and 60% decreases, respectively. There was an increase in the number of percutaneous transluminal coronary angioplasties (33%) and definitive pacemaker implantations (29%). There were 97 admissions to the ICU during P19, in contrast with 78 during P20, a 20% decrease. Visits to the cardiac emergency room (45%) and admissions to the cardiology ward (36%) also decreased. The decrease in oncology consultations was 30%. Chemotherapy sessions decreased from 1,944 to 1,066 (45%), and radiotherapy sessions decreased by 19%. Conclusion COVID-19 has led to a considerable decrease in the number of consultations in outpatient clinics for cardiology, oncology, and other specialties. There was a concerning decrease in the number of cardiac surgeries, chemotherapy sessions, and radiotherapy sessions during the initial weeks of the pandemic. The number of people seeking care in the cardiac emergency room and the number of admissions to the cardiology ward and ICU also decreased, generating concern regarding the evolution and prognosis of these patients with pathologies other than COVID-19 during this pandemic time. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)

https://doi.org/10.36660/abc.20200436 1791 downloads

11.

Yield and morphological attributes of bell pepper fruits under biological fertilizers and application times
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Leal, Ygor Henrique

; Moura, Joana Gomes de

; Silva, Toshik Iarley da

; Dias, Thiago Jardelino

; Leal, Márcia Paloma da Silva

; Ribeiro, João Everthon da Silva

Revista Ceres

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Out 2020, Volume 67 Nº 5 Páginas 374 - 382

Resumo: En | Texto: En | PDF: En

ABSTRACT Bell pepper (Capsicum annuum) is one of the most consumed vegetables around the world. Balanced fertilization is essential for growing this vegetable. The objective of this study was to evaluate the yield and morphological attributes of bell pepper under doses and times of application of biological fertilizers. Two experiments were carried out with applications of biological fertilizers prepared from manure and enriched organic compounds with cattle manure and sheep manure. The experimental design was a randomized complete block design, in a 4 x 3 + 1 factorial scheme, with three replications, referring to doses of biological fertilizers (100, 200, 300 and 400 L ha-1), times of application (0, 30 and 60 days after transplanting - DAT) and control. The evaluated variables were: total fruit weight (TFW), number of commercial fruits (NCF), number of non-commercial fruits (NNCF), fruit weight (FW), fruit diameter (FD), fruit length (FL), resistance of fruit peel (RFP), number of flower buds (NFB) and productivity (P). Biological fertilizers caused positive effects on TFW, NCF, FW and P of bell pepper. The application of cattle manure at 60 DAT and sheep manure at 30 DAT promoted a larger fruit diameter. The FW, FL and RFP were influenced by the doses and times of application of biological fertilizers. The application of biofertilizers is efficient in the production of bell pepper.

https://doi.org/10.1590/0034-737x202067050005 600 downloads

12.

The feasibility and effectiveness of thoracoscopic transdiaphragmatic approach for lung biopsy in rabbits. A randomized study
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Wittmaack, Monica Carolina Nery

; Barros, Felipe Farias Pereira da Câmara

; Silva, Paloma do Espírito Santo

; Matsui, Andresa

; Sembenelli, Guilherme

; Mariano, Renata Sitta Gomes

; Teixeira, Pedro Paulo Maia

; Moraes, Paola Castro

Acta Cirúrgica Brasileira

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2020, Volume 35 Nº 5 elocation e202000501

Resumo: En | Texto: En | PDF: En

Abstract Purpose To assess the feasibility of thoracoscopic transdiaphragmatic approach for biopsy of all lung lobes and to determine the optimal intercostal space (ICS) for biopsy of each lung lobe. Methods Ten rabbits were positioned in dorsal recumbency. Total thoracoscopy lung biopsy was made combined transdiaphragmatic approach and right ICS approaches. A camera port was made in the transdiaphragmatic approach and the instrument port was made of ICS 7 and ICS 9. A pre tied loop ligature was placed to performed a caudal lung lobe biopsy and to simulate biopsies of the others lung lobes. Results Biopsy of the cranial aspect of the right caudal lung lobe was performed at ICS 9. Simulated biopsy of the accessory lung lobe was performed at ICS 9. Simulated lung biopsy of the right cranial and middle lung lobes was performed at ICS 7. The caudal and dorsal aspect of the right caudal lung lobe was not visualized by telescope at transdiaphragmatic approach, and biopsy was not performed. Conclusions Thoracoscopic transdiaphragmatic approach for lung lobes biopsies was a feasible technique, except for the caudal aspect of the right caudal lung lobe. An ideal intercostal port for biopsy of each right lung lobe was determined.

https://doi.org/10.1590/s0102-865020200050000001 564 downloads

13.

Geometric morphometrics of Aedes aegypti populations and study of transmission of arboviral diseases in Barreiras, Brazil
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Arcanjo, Danielle Beatriz Marques Campos

; Vidal, Paloma Oliveira

; Santos, José Yure Gomes dos

; Venancio, Larissa Paola Rodrigues

; Suesdek, Lincoln

; Amorim, Jaime Henrique

Revista Brasileira de Entomologia

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2020, Volume 64 Nº 1 elocation e201960

Resumo: En | Texto: En | PDF: En

Abstract Aedes (Stegomyia) aegypti (A. aegypti) transmits arboviral diseases of high public health importance, including those caused by Zika virus (ZIKV), Dengue virus (DENV), Chikungunya virus (CHIKV) and Yellow fever virus (YFV). Barreiras is a city with 157,638 inhabitants in the West of the State of Bahia, Northeast of Brazil. The climate is dry, with well-determined and concentrated seasons of rains. The city is crossed by a Federal Highway and by the Rio Grande river. In this study, we aimed to understand the dynamics of mosquito vectors and arboviral diseases in Barreiras. We used correlation statistics to investigate a possible relationship among rains, mosquito abundance and transmission of diseases. In addition, as a preliminary population genetics estimate, we used geometric morphometrics to compare mosquitoes from areas limited by a highway and a river. We found that i) infestation occurs in rain-dependent cycles and that ii) both, the river and the highway segregate populations of A. aegypti in different areas of the studied city. Our results indicate that it is necessary to treat anthropic containers with mosquito breading capacity during both, the dry and rain seasons in urban areas similar to Barreiras.

https://doi.org/10.1590/1806-9665-rbent-2019-60 888 downloads

14.

Hospitalization costs and their determining factors among patients undergoing kidney transplantation: a cross-sectional descriptive study
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Barreto, Maynara Fernanda Carvalho

; Dellaroza, Mara Solange Gomes

; Fernandes, Karen Barros Parron

; Pissinati, Paloma de Souza Cavalcante

; Galdino, Maria José Quina

; Haddad, Maria do Carmo Fernandez Lourenço

Sao Paulo Medical Journal

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Dez 2019, Volume 137 Nº 6 Páginas 498 - 504

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: Cost evaluation is a key tool in monitoring expenditure for budget management. It increases the efficiency of possible changes through identifying potential savings and estimating the resources required to make such changes. However, there is a lack of knowledge of the total cost of hospitalization up to the clinical outcome, regarding patients admitted for kidney transplantation. Likewise, there is a lack of data on the factors that influence the amounts spent by hospital institutions and healthcare systems. OBJECTIVES: To describe the costs and determining factors relating to hospitalization of patients undergoing kidney transplantation. DESIGN AND SETTING: Cross-sectional descriptive study with a quantitative approach based on secondary data from 81 patients who were admitted for kidney transplantation at a leading transplantation center in southern Brazil. METHODS: The direct costs of healthcare for patients who underwent kidney transplantation were the dependent variable, and included personnel, expenses, third-party services, materials and medicines. The factors that interfered in the cost of the procedure were indirect variables. The items that made up these variables were gathered from the records of the internal transplantation committee and from the electronic medical records. The billing sector provided information on the direct costs per patient. RESULTS: The estimated total cost of patients’ hospitalization was R$ 1,257,639.11 (US$ 571,010.44). Out of this amount, R$ 1,237,338.31 (US$ 561,793.20) was paid by the Brazilian National Health System and R$ 20,300.80 (US$ 9,217.24) by the transplantation center’s own resources. The highest costs related to the length of hospital stay and clinical complications such as sepsis and pneumonia. CONCLUSIONS: The costs of hospitalization for kidney transplantation relate to the length of hospital stay and clinical complications.

https://doi.org/10.1590/1516-3180.2018.055117092019 890 downloads

15.

Impact of heart rate on reproducibility of heart rate variability analysis in the supine and standing positions in healthy men
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da Cruz, Carlos Janssen Gomes

; Porto, Luiz Guilherme Grossi

; da Silva Rolim, Paloma

; de Souza Pires, Deleon

; Garcia, Giliard Lago

; Molina, Guilherme Eckhardt

Clinics

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2019, Volume 74 elocation e806

Resumo: En | Texto: En | PDF: En

OBJECTIVE: The reliability of heart rate variability (HRV) analysis is not yet fully understood, especially considering different body positions and the mathematical influence of heart rate. The aim of this study was to evaluate the reliability of HRV in supine and standing positions, with and without mathematical adjustment of HRV by the average R-R interval (iRR). METHODS: We evaluated 37 young males (23.1±4 years; 25.1±3 kg/m2). A 5-min segment of the iRR was collected in the supine and standing positions on three occasions separated by 48-hour intervals. Absolute and relative reliability of temporal and spectral indices were assessed by the coefficient of variation (CV) and the intraclass correlation coefficient (ICC), respectively. RESULTS: We did not observe differences in HRV indices in the three occasions in the supine or standing position (p>0.05). Moderate to good reproducibility was observed for temporal and spectral indices of HRV in the supine position (ICC: 0.65-0.89; CV: 0.9-19.8). In the orthostatic position, low to good reproducibility was observed (ICC: 0.35-0.89; CV: 1.1-34.8), with higher ICCs for temporal indices. After mathematical adjustment, only a small modification in HRV reliability was observed in both positions. CONCLUSIONS: In young adult males, the mathematical adjustment of HRV by the average iRR led to a nonsignificant effect on HRV reliability. Additionally, HRV reliability is dependent on body position and the index analyzed. Promising measures in both supine and standing positions include r-MSSD and the HF band (parasympathetic indices).

https://doi.org/10.6061/clinics/2019/e806 965 downloads

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